PPAR gamma Monoclonal Antibody (A3409A)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 419300 | 100 µL | 780,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody specifically recognizes human PPAR gamma1 and 2 and cross reacts with mouse and rat PPAR gamma1 and 2. This antibody does not recognize human PPAR alpha and delta. This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Baculovirus-expressed recombinant human PPAR-gamma-1 (3-108 aa). |
| Host | Ms |
| Clone Number | [A3409A] |
| Genebank | PPARG |
| Isotype | IgG2a |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; physiological saline; , with 0.1% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (20 µg/mL), ChIP Assay (Assay-dependent), ELISA (12 ng/mL), Gel S... |
| Purity | Ammonium sulfate precipitation |
| Conjugation | Unconjugated |
| Storage Conditions | Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
