PARP1 Monoclonal Antibody (123)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 436400 | 100 µg | 598,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein derived from the C-terminal region of human PARP protein. |
| Host | Ms |
| Clone Number | [123] |
| Genebank | PARP1 |
| Isotype | IgG1 |
| Crossreactivity | Dg, Ho, Hu, Ms, Rt, Rhesus Monkey |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Immunocytochemistry (1-2 µg/mL), Western Blot (1-3 µg/mL), Immunoprecipitation (1:100-1:300), Imm... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
