beta Amyloid (1-42) Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 44344 | 25 µg | 582,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Reacts with human Abeta42. No significant cross-reactivity to Abeta40 has been observed. Previous lots have shown no cross reactivity to Abeta43. Cross-reactivity against Abeta42 from mouse, rat, pig, cow, sheep, dog, rabbit, frog and polar bear (100% homology) is expected but has not been tested. The antibody has been used in ELISA. Previous lots of this antibody have been used in dot blots, RIA, and other related assays. Beta amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | DB, EL, IHC, RIA |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide derived from amino acids 36-42 within the C-terminal region of human beta-Amyloid protein |
| Host | Rb |
| Genebank | APP |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7.4, with no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | ELISA (1 µg/mL), Radioimmune assays (Assay-dependent), Dot Blot (Assay-dependent), Functional Ass... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: 44-344 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
