Phospho-EIF2S1 (Ser52) Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 44728G | 100 µL | 578,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Immunogen | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human eIF2a that contains serine 52. This region is conserved among many species including rat,... |
| Host | Rb |
| Genebank | EIF2S1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Yeast |
| Clonality | Pab |
| Format | Liquid; Dulbecco's PBS; pH 7.3, with 1mg/mL BSA and 0.05% sodium azide |
| Working Dilution | Immunocytochemistry (Assay-dependent), Western Blot (1:1,000) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: 44-728G |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
