Aurora A Monoclonal Antibody (35C1)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 458900 | 100 µg | 588,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein derived from the full length of human Aurora A Kinase protein |
| Host | Ms |
| Clone Number | [35C1] |
| Genebank | AURKA |
| Isotype | IgG1 |
| Crossreactivity | Bo, Dg, Ho, Hu, Ms, Primate, Pg, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (1-3 µg/mL), Immunoprecipitation (5 µg), Immunocytochemistry (1-2 µg/mL) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: 45-8900 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
