H3K27me3S28ph Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
491015 100 µL 644,00 Add

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Product Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.

Category Antibody
Supplier ThermoFisher
Application ChIP, EL, ICC, IP, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Raised against histone H3 containing the trimethylated lysine 27 and the phosphorylated serine 28 (H3K27me3S28p), using a KLH conjugated synthetic peptide.
Host Rb
Genebank H3C15
Isotype IgG
Crossreactivity Hu
Clonality Pab
Format Liquid; whole serum; , with <0.1% sodium azide
Working Dilution Western Blot (1:250), ELISA (1:100-1:500), Immunocytochemistry (1:200), ChIP Assay (1 µL/ChIP), I...
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Shipped on dry ice - extra freight charge will occur. Alternative CatNo: 49-1015
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Dry Ice
Material Safety Data Sheet Download PDF