Histone H3 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 491038 | 100 µL | 614,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, WB |
| Regulatory Status | RUO |
| Immunogen | Raised against the C-term of human HIST3H3. |
| Host | Rb |
| Genebank | H3C1 |
| Isotype | IgG |
| Crossreactivity | Hu, Zebrafish |
| Clonality | Pab |
| Format | Liquid; whole serum; , with <0.1% sodium azide |
| Working Dilution | ChIP Assay (1-10 µg/1x10^6 cells), ELISA (1:10,000), Western Blot (1:500) |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: 49-1038 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
