Smooth Muscle Myosin Monoclonal Antibody (SMMS-1), Alexa Fluor™ 488, eBioscience™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
53-6400-82 | 100 µg | 588,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Description: This SMMS-1 monoclonal antibody reacts with both isoforms of the human smooth muscle myosin heavy chain (SM1 and SM2) structural proteins, which are components of the contractile apparatus in smooth muscle cells. Smooth muscle myosin heavy chains are expressed by myoepithelial cells and also serve as the terminal differentiation marker for smooth muscle cells. In normal breast tissue, myoepithelial cells compose the outer layer of the lumen lining. In benign and in situ breast lesions, the intact myoepithelial layer stains with SMMS-1 and the loss of this staining indicates invasive cancer. This SMMS-1 antibody has also been reported to cross-react with bovine, canine, feline, and rat smooth muscle myosin heavy chains. Applications Reported: This SMMS-1 antibody has been reported for use in microscopy, immunocytochemistry, immunohistochemical staining of frozen tissue sections, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. Applications Tested: This SMMS-1 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 30 µg/mL. It is recommended that the antibody be carefully titrated for optimal performanc
Category | Antibody |
Supplier | ThermoFisher |
Application | ICC, IHC |
Regulatory Status | RUO |
Host | Ms |
Clone Number | [SMMS-1] |
Genebank | MYH11 |
Isotype | IgG1,k |
Crossreactivity | Bo, Dg, Ca, Hu, Rt |
Clonality | Mab |
Format | Liquid; PBS; pH 7.2, with 0.09% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Immunohistochemistry (Frozen) (30 µg/mL), Immunocytochemistry (Assay-Dependent), Immunohistochemi... |
Purity | Affinity chromatography |
Conjugation | Alexa Fluor 488 |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: 53640082 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |