H3K4me2 Recombinant Rabbit Monoclonal Antibody (24H8L19), ChIP-Verified
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
701764 | 100 µg | 604,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Since it is highly conserved across species, the antibody may react with many other species. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence ce
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, ICC, WB |
Regulatory Status | RUO |
Immunogen | Methylated peptide (Lys4) corresponding to human Histone H3 (aa 4-10) |
Host | Rb |
Clone Number | [24H8L19] |
Genebank | H3C1 |
Isotype | IgG |
Crossreactivity | Hu, Yeast |
Clonality | Recombi |
Format | Liquid; PBS; pH 7.2, with 0.09% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Peptide array (0.25 µg/mL), ChIP Assay (1-5 µg), Western Blot (1-2 µg/mL), Immunocytochemistry (1... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |