CD38 Monoclonal Antibody (90), Pacific Blue™
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| A15393 | 100 µg | 738,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Native purified Cd38 from mouse bone marrow pre-B cells. |
| Host | Rt |
| Clone Number | [90] |
| Genebank | CD38 |
| Isotype | IgG2a,k |
| Crossreactivity | Ms |
| Clonality | Mab |
| Format | Liquid; PBS; , with <0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Flow Cytometry (0.2 µg/1x10^6 cells) |
| Purity | purified |
| Conjugation | Pacific Blue |
| Storage Conditions | Cold Room (2 to 8 C) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
