GLP-1 Monoclonal Antibody (03)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
ABS0460302 | 400 µL | 924,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Specificity: ABS 046-03-02 binds GLP-1 (1-37), GLP-1 (7-37) and GLP-1 (9-37). This antibody shows 0-16% cross-Specificity with C-terminally amidated GLP-1 in various circumstances. Reactivity: ABS 046-03-02 binds free GLP-1 (1-37), GLP-1 (7-37) and GLP-1 (9-37) in solution. Two different ELISA sandwich setups can be used for measuring non-amidated GLP-1 forms: The first uses ABS 046-03 as a capture antibody with biotinylated detection antibody ABS 033-10-02. This shows ~5% cross-reactivity with C-terminally amidated GLP-1. The second combination uses HYB 147-12 as a capture antibody with biotinylated detection antibody ABS 046-03-02, resulting in ~16% cross-reactivity with C-terminally amidated GLP-1. Results show detection limits of 44 pmol/L which is 10-20 times higher than the basal concentration of GLP-1, so the assays have to be optimized. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competen
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, WB |
Regulatory Status | RUO |
Immunogen | Synthetic GLP-1(9-37) adsorbed onto aluminum hydroxide gel. |
Host | Ms |
Clone Number | [03] |
Genebank | GCG |
Isotype | IgG1,k |
Crossreactivity | Hu, Ma, Ms, Rt |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 15mM sodium azide |
Concentration | 1.03 mg/mL |
Working Dilution | Western Blot (Assay-dependent), ELISA (Assay-dependent) |
Purity | Protein A/G |
Conjugation | Unconjugated |
Storage Conditions | 4° C, store in dark |
Disclaimer | Alternative CatNo: ABS 046-03-02 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |