IL-2 Monoclonal Antibody (297C16F11)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
AHC0722 | 500 µg | 600,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Purity is >95% by SDS-PAGE. Kd: 1.8 x 10^-9 This product can inhibit the binding of IL-2 on p55 receptor. Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Category | Antibody |
Supplier | ThermoFisher |
Application | DB, IHC, N |
Regulatory Status | RUO |
Immunogen | Recombinant human IL-2. |
Host | Ms |
Clone Number | [297C16F11] |
Genebank | IL2 |
Isotype | IgG2a,k |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with no preservative |
Concentration | 1 mg/mL |
Working Dilution | Dot Blot (Assay-dependent), Inhibition Assays (Assay-dependent), Neutralization (Assay-dependent)... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |