EIF2S1 Monoclonal Antibody (EIF2-alpha)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| AHO0802 | 100 µg | 666,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody recognizes the alpha subunit of eukaryotic translation initiation factor 2 (EIF2-alpha). Recommended positive control are human Jurkat, CEM, and HeLa cells; mouse 3T3L1 cells; and rat PC-12 cells. EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant human eIF-2-alpha. |
| Host | Ms |
| Clone Number | [EIF2-alpha] |
| Genebank | EIF2S1 |
| Isotype | IgG1 |
| Crossreactivity | Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (1:500-1:1,000), Immunohistochemistry (Paraffin) (1:10-1:50), Immunocytochemistry (1... |
| Purity | Protein A/G |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
