IL-6 Receptor Monoclonal Antibody (B-R6)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| AHR0061 | 100 µg | 682,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC, IHC, IP, N |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | CHO cells transfected with cDNA corresponding to the gp80 IL-6 receptor gene. |
| Host | Ms |
| Clone Number | [B-R6] |
| Genebank | IL6R |
| Isotype | IgG1,k |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.2, with no preservative |
| Concentration | 4.0 mg/mL |
| Working Dilution | Neutralization (Assay-dependent), ELISA (Assay-dependent), Flow Cytometry (Assay-dependent), Immu... |
| Purity | purified |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
