Complement C5b Monoclonal Antibody (aE11)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| DIA0110102 | 400 µL | 1'052,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
DIA 011-01-02 binds both membrane-bound MAC and fluid-phase SC5b-9 complexes from human, porcine, baboon and equine samples. DIA 011-01-02 has been successfully used in ELISA and IHC applications. This antibody is not recommended for Western blotting as the epitope is destroyed during the process. C5b-9 is also known as the TCC. TCC consists of C5b, C6, C7, C8 and C9. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The complex contains neoantigens that are absent from the individual native components and the monoclonal antibody DIA 011-01 is directed against a neoepitope exposed in C9 when incorporated into TCC.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IHC |
| Regulatory Status | RUO |
| Immunogen | Purified C5b-9. |
| Host | Ms |
| Clone Number | [aE11] |
| Genebank | C5 |
| Isotype | IgG2a,k |
| Crossreactivity | Ho, Hu, Primate, Pg |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 15mM sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Frozen) (Assay-dependent), Immunohistochemistry (Paraffin) (Assay-dependent... |
| Purity | Protein A/G |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: DIA 011-01-02 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
