SOX2 Monoclonal Antibody (20G5), DyLight™ 488
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA1014D488 | 100 µL | 514,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-014-D488 has been successfully used in ICC/IF applications with human and mouse samples. MA1-014-D488 can be used for immunofluorescence analysis of LIN28 in human iPSCs. SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC |
| Regulatory Status | RUO |
| Immunogen | Full-length human recombinant protein expressed in bacteria |
| Host | Ms |
| Clone Number | [20G5] |
| Genebank | SOX2 |
| Isotype | IgG1,k |
| Crossreactivity | Hu, Ms |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with proprietary stabilizer and 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:100) |
| Purity | Protein A |
| Conjugation | DY 488 |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: MA1-014-D488 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
