LIN28A Monoclonal Antibody (14E6-4E6)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA1016 | 100 µg | 536,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-016 has been successfully used in Western blot, immunofluorescence, ChIP, flow cytometry, IHC (P) and immunoprecipitation applications on human and mouse samples. Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, FC, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Full-length human recombinant protein expressed in bacteria |
Host | Ms |
Clone Number | [14E6-4E6] |
Genebank | LIN28A |
Isotype | IgG2a |
Crossreactivity | Hu, Ms |
Clonality | Mab |
Format | Liquid; PBS; , with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Immunocytochemistry (1:50-1:200), Western Blot (1:1,000), Immunoprecipitation (5 µg), Flow Cytome... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | -20°C |
Disclaimer | Alternative CatNo: MA1-016 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |