SSEA3 Monoclonal Antibody (MC-631), DyLight™ 488
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA1020D488 | 100 µL | 524,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-020-D488 has been successfully used in ICC/IF and flow cytometry applications on human samples. MA1-020-D488 can be used for immunofluoresence analysis of SSEA3 in human iPSCs. SSEA-3 (stage-specific embryonic antigen 3) is a cell surface antigen, expressed along with SSEA-4, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells, and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC, ICC |
| Regulatory Status | RUO |
| Immunogen | Fischer rat immunized with 4-8 cell stage mouse embryos |
| Host | Rt |
| Clone Number | [MC-631] |
| Isotype | IgM |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; PBS; , with proprietary stabilizer and 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:10-1:100), Flow Cytometry (1:50-1:500), ELISA (1 µg/mL) |
| Purity | Affinity chromatography - MBP |
| Conjugation | DY 488 |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: MA1-020-D488 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
