SSEA1 Monoclonal Antibody (MC-480), DyLight™ 550
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA1022D550 | 100 µL | 476,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-022-D550 has been successfully used in flow cytometry on mouse and human samples. CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | BALB/c mouse immunized with F9 teratocarcinoma stem cells (X-irradiated). |
Host | Ms |
Clone Number | [MC-480] |
Genebank | FUT4 |
Isotype | IgM |
Crossreactivity | Hu, Ms |
Clonality | Mab |
Format | Liquid; PBS; , with proprietary stabilizer and 0.02% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Flow Cytometry (1:50-1:500) |
Purity | Affinity chromatography - MBP |
Conjugation | DY 550 |
Storage Conditions | 4° C, do not freeze |
Disclaimer | Alternative CatNo: MA1-022-D550 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |