Dynein Monoclonal Antibody (74.1)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA1070 | 100 µg | 620,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-070 detects two isoforms of the ~74 kDa polypetide of cytoplasmic dynein. MA1-070 has been successfully used in Western blot immunofluorescence, and immunoprecipitation procedures. In Western blot analysis of HeLa cell lysate this antibody detects a ~74 kDa protein representing cytoplasmic dynein. The MA1-070 immunogen is purified bovine brain cytoplasmic dynein. The directed movement of membrane-bounded organelles is an important process for various cellular functions including membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a ubiquitous minus end-directed microtubule-based motor protein, is believed to be responsible for the retrograde transport of membranous organelles from the synapse to the cell body in fast axonal transport. The cytoplasmic dynein complex is composed of two ~530 kDa heavy chains, and intermediate chains of ~74 kDa and ~53-59 kDa.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Purified bovine brain cytoplasmic dynein. |
| Host | Ms |
| Clone Number | [74.1] |
| Genebank | DYNLL1 |
| Isotype | IgG2b |
| Crossreactivity | Bo, Hu, Many, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with 1mg/mL BSA and 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (1 µg/mL), Immunoprecipitation (Assay-dependent), Flow Cytometry (1-2 µg/test), Immu... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: MA1-070 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
