NF1 Monoclonal Antibody (McNFn27a)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA1084 | 200 µg | 572,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-084 detects neurofibromin in human, rat and mouse cells. MA1-084 has been successfully used in Western blot, procedures. By Western blot, this antibody detects a ~230-260 kDa protein. The MA1-084 immunogen is a synthetic peptide corresponding to the N-terminal residues 27-41 of human neurofibromin. The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Category | Antibody |
Supplier | ThermoFisher |
Application | AP, EL, ICC, IP, WB |
Regulatory Status | RUO |
Immunogen | Synthetic peptide corresponding to the N-terminal residues 27-41 of human neurofibromin. |
Host | Ms |
Clone Number | [McNFn27a] |
Genebank | NF1 |
Isotype | IgG1 |
Crossreactivity | Hu, Ms, Rt |
Clonality | Mab |
Format | Liquid; PBS; , with 1mg/mL BSA and 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Affinity Purification (Assay-dependent), ELISA (Assay-dependent), Immunoprecipitation (Assay-depe... |
Purity | Protein G |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA1-084 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |