SSEA1 Monoclonal Antibody (MEM-158), APC
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA110106 | 100 Tests | 476,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody will not cross-react with porcine, bovine or sheep. CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | Human granulocytes |
Host | Ms |
Clone Number | [MEM-158] |
Genebank | FUT4 |
Isotype | IgM |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; TBS; pH 8, with 0.2% BSA and 15mM sodium azide |
Working Dilution | Flow Cytometry (10 µL/1x10^6 cells) |
Purity | Size-exclusion chromatography |
Conjugation | APC |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: MA1-10106 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |