CD80 Monoclonal Antibody (16-10A1)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA110287 | 100 µg | 262,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, IHC, IP |
Regulatory Status | RUO |
Immunogen | CD80-transfected CHO cell line |
Host | Hm |
Clone Number | [16-10A1] |
Genebank | CD80 |
Isotype | IgG2 |
Crossreactivity | Dg, Ms |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 15mM sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Flow Cytometry (1-4 µg/mL), Immunoprecipitation (Assay-Dependent), Immunohistochemistry (Frozen) ... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C, do not freeze |
Disclaimer | Alternative CatNo: MA1-10287 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |