RNaseL Monoclonal Antibody (2E9)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA116575 | 100 µL | 742,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody does not react with mouse or rat samples. A virally induced endoribonuclease, RNase L is the terminal factor of the anti-viral action of interferon. Activation of RNase L results in inhibition of viral proliferation. Activation of RNase L has also been determined to degrade RNA, thus, initiating a cellular stress response, inducing apoptosis. Since mutations in RNase L relate to an increased incidence of prostate cancer, the activation of RNase L functions in counteracting prostate cancer, via apoptosis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Purified, full-length, recombinant, human RNaseL produced in insect cells. |
| Host | Ms |
| Clone Number | [2E9] |
| Genebank | RNASEL |
| Isotype | IgG1,k |
| Crossreactivity | Hm, Hu, Primate |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 1.0 mg/mL |
| Working Dilution | ELISA (1:100-1:2,000), Western Blot (1:1,000-1:4,000), Immunohistochemistry (Paraffin) (1:200-1:1... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA1-16575 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
