p300 Monoclonal Antibody (RW105)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA116622 | 100 µL | 748,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: HeLa nuclear extract. EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, FC, ICC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Fusion protein containing residues 1572-2371 of human KAT3B/p300. |
| Host | Ms |
| Clone Number | [RW105] |
| Genebank | EP300 |
| Isotype | IgG1,k |
| Crossreactivity | Hu, Ms, Mustelid, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (1:250-1:1,000), Immunomicroscopy (Assay-Dependent), ChIP Assay (Assay-Dependent), I... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA1-16622 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
