rRNA Monoclonal Antibody (Y10b)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA116628 | 100 µL | 654,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This clone recognizes both the large and the small subunit of rRNA from all eukaryotic cells. rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer's disease.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP |
| Regulatory Status | RUO |
| Immunogen | Whole 5.8S ribosomal RNA. |
| Host | Ms |
| Clone Number | [Y10b] |
| Isotype | IgG3,k |
| Crossreactivity | Multi |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (2.5 µg/mL), Immunocytochemistry (1-3 µg/mL), Immunoprecipitation (10 µL/lysate), ... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: MA1-16628 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
