CD9 Monoclonal Antibody (IVA50)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA119301 | 100 µg | 486,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, IP, WB |
Regulatory Status | RUO |
Immunogen | Bovine thrombocytes. |
Host | Ms |
Clone Number | [IVA50] |
Genebank | CD9 |
Isotype | IgG2 |
Crossreactivity | Bo, Hu |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 15mM sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Western Blot (1 µg/mL), Immunoprecipitation (Assay-dependent), Flow Cytometry (Assay-dependent) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C, do not freeze |
Disclaimer | Alternative CatNo: MA1-19301 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |