CD41 Monoclonal Antibody (HIP2)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA119382 | 100 µg | 489,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody reacts with beta (b) subunit of CD41 glycoprotein (light chain; 23 kDa). CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, IHC |
| Regulatory Status | RUO |
| Immunogen | Human CD41b. |
| Host | Ms |
| Clone Number | [HIP2] |
| Genebank | ITGA2B |
| Isotype | IgG3 |
| Crossreactivity | Hu, Primate |
| Clonality | Mab |
| Format | Liquid; TBS; pH 8.0, with 15mM sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (1-4 µg/mL), Immunohistochemistry (Frozen) (Assay-dependent) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: MA1-19382 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
