CD147 (soluble) Monoclonal Antibody (MEM-M6/2)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA119410 | 100 µg | 394,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody recognizes the extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, IHC |
Regulatory Status | RUO |
Immunogen | A soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the entire extracellular region of CD147 fused to the DNA coding for the hinge region, CH2 and CH3 domain of huma... |
Host | Ms |
Clone Number | [MEM-M6/2] |
Genebank | BSG |
Isotype | IgG2b |
Crossreactivity | Hu, Pg |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 15mM sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Immunohistochemistry (Paraffin) (10 µg/mL), Flow Cytometry (4 µg/mL) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C, do not freeze |
Disclaimer | Alternative CatNo: MA1-19410 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |