Plasminogen Monoclonal Antibody (8E7)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA120081 | 500 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-20081 detects plasminogen in human samples. Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200 mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.
Category | Antibody |
Supplier | ThermoFisher |
Application | AP, EL, IHC |
Regulatory Status | RUO |
Immunogen | Purified, full length, native, human plasminogen protein. |
Host | Ms |
Clone Number | [8E7] |
Genebank | PLG |
Isotype | IgG1 |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 0.09% sodium azide |
Concentration | 9 mg/mL |
Working Dilution | Affinity Purification (Assay-dependent), ELISA (Assay-dependent), Immunohistochemistry (Paraffin)... |
Purity | IgG fraction |
Conjugation | Unconjugated |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: MA1-20081 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |