Phospho-AKT1 (Ser473) Monoclonal Antibody (104A282)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA120325 | 50 µg | 716,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-20325 detects phospho-AKT1 (pS473) in human and mouse samples. AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | This monoclonal antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 473 of human Akt1. |
| Host | Ms |
| Clone Number | [104A282] |
| Genebank | AKT1 |
| Isotype | IgG1 |
| Crossreactivity | Ck, Hu, Ms, Zebrafish |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:200-1:250), Western Blot (1-2 µg/mL), Immunocytochemistry (2 µ... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-20325 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
