ATF1 Monoclonal Antibody (ATF1 2A9/8)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA121313 | 100 µg | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The predicted molecular weight of MA1-21313 is 60 kDa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
Category | Antibody |
Supplier | ThermoFisher |
Application | IP, WB |
Regulatory Status | RUO |
Immunogen | ATF1 |
Host | Ms |
Clone Number | [ATF1 2A9/8] |
Genebank | ATF1 |
Isotype | IgG2a |
Crossreactivity | Hu, Yeast |
Clonality | Mab |
Format | Liquid; PBS; pH 7.2, with no preservative |
Concentration | 0.7 mg/mL |
Working Dilution | Western Blot (Assay-dependent), Immunoprecipitation (Assay-dependent) |
Purity | IgG fraction |
Conjugation | Unconjugated |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Disclaimer | Alternative CatNo: MA1-21313 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |