Myc Tag Monoclonal Antibody (Myc.A7), DyLight™ 680
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA121316D680 | 50 µL | 350,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-21316-D680 has been successfully used in immunofluorescence and Western blot applications. DyLight 680 has an excitation/emission of 692/712 nm. Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide: EQKLISEEDL (Myc). |
| Host | Ms |
| Clone Number | [Myc.A7] |
| Isotype | IgG1 |
| Crossreactivity | Tag |
| Clonality | Mab |
| Format | Liquid; PBS; , with proprietary stabilizer and 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:25-1:100), Western Blot (1:500-1:1,000) |
| Purity | Protein A |
| Conjugation | DY 680 |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: MA1-21316-D680 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
