Cholera Toxin beta Monoclonal Antibody (3D11)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA121550 | 100 µg | 658,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL |
Regulatory Status | RUO |
Immunogen | Purified beta subunit of cholera toxin. |
Host | Ms |
Clone Number | [3D11] |
Isotype | IgG2b |
Crossreactivity | Bacteria |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 0.09% sodium azide |
Concentration | 3.1 mg/mL |
Working Dilution | ELISA (1:1,000,000) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: MA1-21550 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |