TNNI2 Monoclonal Antibody (7G2)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA122704 | 100 µg | 602,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-22704 detects skeletal muscle Troponin I in Human samples. This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.
Category | Antibody |
Supplier | ThermoFisher |
Application | AP, EL, WB |
Regulatory Status | RUO |
Immunogen | Full length native protein (purified) (Human). |
Host | Ms |
Clone Number | [7G2] |
Genebank | TNNI2 |
Isotype | IgG2b |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 0.09% sodium azide |
Concentration | 5.3 mg/mL |
Working Dilution | ELISA (Assay-dependent), Western Blot (Assay-dependent), Affinity Purification (Assay-dependent) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C, do not freeze |
Disclaimer | Alternative CatNo: MA1-22704 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |