RAD51 Monoclonal Antibody (14B4)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA123271 | 100 µL | 668,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
A suggested positive control for this product is T24. RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Full length Rad51 protein (amino acids 1-338) expressed in E. coli. |
| Host | Ms |
| Clone Number | [14B4] |
| Genebank | RAD51 |
| Isotype | IgG2b |
| Crossreactivity | Ck, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and no preservative |
| Concentration | 1.0 mg/mL |
| Working Dilution | Western Blot (1:500-1:3,000), Immunoprecipitation (Assay-dependent), Immunocytochemistry (1:100-1... |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-23271 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
