CXCR1 Monoclonal Antibody (42705.111)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA124668 | 100 µg | 658,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: human spleen. Human CXCR1 reacts with CXCR1 transfected cells and not with the parent cell line by flow cytometry. Thw antibody shows no cross-reactivity with human CXCR2. Endotoxin level is less than 10 ng per mg antibody as determined by the LAL method. CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, IHC, N |
| Regulatory Status | RUO |
| Immunogen | Human CXCR1 transfected NSO mouse myeloma cells. |
| Host | Ms |
| Clone Number | [42705.111] |
| Genebank | CXCR1 |
| Isotype | IgG2a |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; PBS; , with 5% trehalose and no preservative |
| Concentration | 0.5 mg/mL |
| Working Dilution | Flow Cytometry (10 µg/mL), Inhibition Assays (0.1-0.3 µg/mL), Neutralization (Assay-dependent), I... |
| Purity | purified |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-24668 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
