Oncostatin M Monoclonal Antibody (17001.31)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA124832 | 100 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-24832 will not react with mouse. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, N, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant, full length human protein expressed in E. coli. |
| Host | Ms |
| Clone Number | [17001.31] |
| Genebank | OSM |
| Isotype | IgG2a |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; PBS; , with 5% trehalose and no preservative |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (1-2 µg/mL), ELISA (0.5-1 µg/mL), Neutralization (0.1-5 µg/mL) |
| Purity | purified |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-24832 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
