PKC alpha Monoclonal Antibody (133)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA125286 | 1 mL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-25286 detects PKC alpha from a wide range of mammal species samples. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide corresponding to the C-terminus residues P Q F V H P I L Q S A V of PKC alpha. |
| Host | Ms |
| Clone Number | [133] |
| Genebank | PRKCA |
| Isotype | IgG2a |
| Crossreactivity | Hu, Ma, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; Tissue culture supernatant, with 0.1% sodium azide |
| Working Dilution | Immunohistochemistry (Frozen) (1:10), Western Blot (1:10-1:500) |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-25286 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
