PRMT1 Monoclonal Antibody (PRMT1-171)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA125468 | 50 µL | 598,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Increased expression of PRMT1 may play a role in various types of cancer.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Full length PRMT1. |
| Host | Ms |
| Clone Number | [PRMT1-171] |
| Genebank | PRMT1 |
| Isotype | IgG1 |
| Crossreactivity | Bo, Dg, Ck, Hm, Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; 0.01M PBS; pH 7.4, with 15mM sodium azide |
| Concentration | 2.5 mg/mL |
| Working Dilution | Immunoprecipitation (Assay-dependent), Western Blot (2 µg/mL), ELISA (Assay-dependent), Immunocyt... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-25468 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
