PRMT5 Monoclonal Antibody (PRMT5-21)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA125470 | 50 µL | 684,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: G361. PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, WB |
| Regulatory Status | RUO |
| Immunogen | Fusion of mouse myeloma cells and splenocytes from mice immunized with PRMT5 containing the C-terminal region of the Human PRMT5 (residues 315-637). |
| Host | Ms |
| Clone Number | [PRMT5-21] |
| Genebank | PRMT5 |
| Isotype | IgG2a |
| Crossreactivity | Bo, Dg, Ck, Hm, Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; 0.01M PBS; pH 7.4, with 15mM sodium azide |
| Concentration | 2.4 mg/mL |
| Working Dilution | ELISA (Assay-dependent), Western Blot (2 µg/mL), ChIP Assay (2.5 µg/10^6 cells) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA1-25470 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
