CD15 Monoclonal Antibody (28)


Catalog Number Pack Size List Price* Quantity
MA134583 100 μg 740,00 Add

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Product Description

MA1-34583 detects CD15 from human samples. CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Category Antibody
Supplier ThermoFisher
Application FC, IHC, IP
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Cell preparation: Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates.
Host Ms
Clone Number [28]
Genebank FUT4
Isotype IgM
Crossreactivity Hu
Clonality Mab
Format Liquid; PBS; , with no preservative
Concentration 1 mg/mL
Working Dilution Flow Cytometry (Assay-dependent), Immunoprecipitation (Assay-dependent), Immunohistochemistry (Fr...
Purity IgG fraction
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: MA1-34583
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF