Progesterone Receptor Monoclonal Antibody (Alpha PR6)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA1411 | 100 µg | 634,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-411 reacts with high affinity to the B form of the progesterone receptor from human, mouse, rat, rabbit, bovine, ovine, chicken, and guinea pig tissues. This antibody does not cross-react with estrogen receptor or glucocorticoid receptor. MA1-411 has been successfully used in Western blot, immunocytochemical, immunohistochemical and immunoprecipitation procedures. By Western blot, this antibody detects a 110 kDa protein representing the B form of the PR in chickens." The MA1-411 immunogen is progesterone receptor purified from chick oviduct cytosol. Reconstitute with PBS. The progesterone receptor (PR) is a member of the steroid family of nuclear receptors. The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites. PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory
Category | Antibody |
Supplier | ThermoFisher |
Application | ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Progesterone receptor purified from chick oviduct cytosol. |
Host | Ms |
Clone Number | [Alpha PR6] |
Genebank | PGR |
Isotype | IgG2a |
Crossreactivity | Bo, Ck, Gp, Hu, Ms, Sh, Rb, Rt |
Clonality | Mab |
Format | Lyophilized; PBS; , with 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Immunoprecipitation (Assay-dependent), Western Blot (1 µg/mL), Immunohistochemistry (Paraffin) (5... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA1-411 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |