CD36 Monoclonal Antibody (D-2712)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA146000 | 100 µL | 612,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody does not react with human samples. CD36 (fatty acid translocase, FAT) is an 88 kDa, ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similar to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. Further, CD36 may function as a cell adhesion molecule and directly mediates cyto-adherence of Plasmodium falciparum parasitized erythrocytes. Mutations in the CD36 gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the CD36 protein have been found.
Category | Antibody |
Supplier | ThermoFisher |
Application | IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Adenovirus expressing recombinant mouse CD36. |
Host | Ms |
Clone Number | [D-2712] |
Genebank | CD36 |
Isotype | IgA,k |
Crossreactivity | Ms, Rt |
Clonality | Mab |
Format | Liquid; PBS; , with 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Western Blot (1:500), Immunoprecipitation (10-20 µg), Immunohistochemistry (Paraffin) (1:100-1:250) |
Purity | Protein G |
Conjugation | Unconjugated |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Disclaimer | Alternative CatNo: MA1-46000 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |