HIF-2 alpha Monoclonal Antibody (ep190b), Biotin
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA146459 | 100 µL | 684,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: antigen standard for EPAS1 (transient overexpression lysate). HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide corresponding to residues 535-631 of human HIF-2 alpha. |
| Host | Ms |
| Clone Number | [ep190b] |
| Genebank | EPAS1 |
| Isotype | IgG1 |
| Crossreactivity | Bo, Hm, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with no preservative |
| Concentration | 0.89 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:150-1:300), Western Blot (1:500), ELISA (Assay-Dependent), Imm... |
| Purity | Protein G |
| Conjugation | Biotin |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: MA1-46459 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
