AHR Monoclonal Antibody (RPT9)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA1513 | 100 µL | 624,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-513 detects the aryl hydrocarbon receptor (AhR) from human, mouse, and rat cells. MA1-513 has been successfully used in immunoprecipitation, chromatin immunoprecipitation, immunocytochemistry, immunohistochemistry, immunofluorescence, and gel shift procedures. This antibody specifically immunoprecipitates a single ~95 kDa protein representing AhR from Hepa 1 cytosol. Although MA1-513 can be used in Western blotting procedures, MA1-514 (clone RPT1) is recommended for this procedure. The MA1-513 immunogen is a synthetic peptide corresponding to residues R(12) K R R K P(17) V(22) K P I P A E G I K(31) of mouse AhR. AHR (Ah Receptor) belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM. AHR contains an N-terminal sequence of approximately 200 amino acids termed the PAS domain. AHR, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene. The gene for AHR encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450, and its ligands included
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, FC, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Synthetic peptide corresponding to residues R(12) K R R K P(17) V(22) K P I P A E G I K(31) of mouse AhR. |
Host | Ms |
Clone Number | [RPT9] |
Genebank | AHR |
Isotype | IgG3,k |
Crossreactivity | Hu, Ms, Rt |
Clonality | Mab |
Format | Liquid; , with 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Gel Shift (Assay-dependent), ChIP Assay (1:100), Immunocytochemistry (Assay-dependent), Immunohis... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA1-513 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |