Hepatitis B Virus Core Antigen Monoclonal Antibody (13A9)

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Product Description

MA1-7606 detects HBcAg from virus samples. MA1-7606 has been successfully used in ELISA, Immunoprecipitation, Western Blot and Immunohistochemistry procedures. The MA1-7606 immunogen is a purified recombinant HBcAg core protein. The epitope corresponds to residues 135-140. The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus