CD45 Monoclonal Antibody (YKIX716.13), FITC
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA180304 | 100 µg | 824,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Rat anti Dog CD45 antibody, clone YKIX716.13 recognizes canine CD45 also known as leukocyte common antigen lustered as Canine CD45 in the First Canine Leukocyte Antigen Workshop (CLAW). CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | Canine thymocytes. |
Host | Rt |
Clone Number | [YKIX716.13] |
Genebank | PTPRC |
Isotype | IgG2b |
Crossreactivity | Dg |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 1% BSA and 0.09% sodium azide |
Concentration | 0.1 mg/mL |
Working Dilution | Flow Cytometry (Neat - 1:5) |
Purity | Protein G |
Conjugation | FITC |
Storage Conditions | 4°C or -20°C if preferred, store in dark |
Disclaimer | Alternative CatNo: MA1-80304 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |