CD90 Monoclonal Antibody (OX-7), PE

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Product Description

This antibody recognizes rat and mouse CD90, also known as Thy1.1, expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, T lymphocytes (mouse), immature B cells (rat) and connective tissues. Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark. Once reconstituted, this product has a shelf life of approx. 6 months. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.