CD8 Monoclonal Antibody (vpg9), PE
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA181034 | 100 Tests | 824,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody creacts with the alpha and beta chains of CD8. This antibody does not react with human. Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Mouse anti Cat CD8 alpha/beta antibody, clone vpg9 recognizes the feline homolog of human CD8. Clone vpg 9 specifically recognizes an epitope associated with the alpha/beta complex of the CD8 heterodimer (Shimojima et al. 1998). Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | Feline thymocytes. |
Host | Ms |
Clone Number | [vpg9] |
Genebank | CD8A |
Isotype | IgG1 |
Crossreactivity | Ca |
Clonality | Mab |
Format | Lyophilized; PBS; pH 7.4, with 1% BSA and 0.09% sodium azide |
Working Dilution | Flow Cytometry (Neat) |
Purity | purified |
Conjugation | PE |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: MA1-81034 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |